As Ray Peat says, estrogen is an amphetamine. It is a free radical which combines with neurotransmitters which are basically a form of catecholamine, to form estradiol-catechols. This is particularly the excitotoxic part to your brain.
Unless balanced with shitloads of progesterone, which is a neuralator, myelinator and whilst amplifying estrogen's effects, attenuates excessive stimulation of ERs (estrogen receptors), you're just fucking yourself over like you did with alcohol.
(Edited 43 seconds later.)
@previous (C)
Progesterone, in my view, can, especially with depressive illnesses. Estrogens are basically like asking to be afflicted with chemically induced mania, though.
@previous (Sophie)
an expert on mental health, you are
@762,910 (Sophie)
This is nonsense, Mr. Gillon.