Topic: CLOWNS & DRUGS
Nonverbal started this discussion 10 years ago #56,222
RAT PARK AND OTHER CHILDREN'S STORIES.
There is a myth going around that dope is such a huge joy that if you try just one dose of it, it will be so pleasurable that you will get hooked for life. We have all heard of the experiments with the lab rats, where rats were put in cages and given levers to press. Each time they pressed the lever, they got a dose of dope. And the rats just pressed the levers all of the time, and stayed high until they died. They wouldn't even stop to eat; they just doped themselves to death. The implication was that the dope was so good, so pleasurable, such an ecstatic high, that the rats couldn't help but get addicted and kill themselves on the stuff.
It turns out that those experiments were all wrong. The researchers who conducted them weren't cheating; they were honest men trying to get good results. They just made one huge mistake: they ignored the true nature of rats. It turns out that rats are very sociable animals, and they just can't stand being held in solitary confinement, like the rats in those experiments were. For both rats and humans, solitary confinement is pure torture.
Some other researchers tried a new experiment: they created a "Rat Park". They fenced a big, natural area, with shrubs and grass, and plenty of space, and put in a small tribe of rats. Then they gave the rats two bowls of water that they could drink from. One contained morphine, and the other didn't. They could drink all they wanted, at any time they wanted. After a few tries, to see what was what, the rats would never drink from the morphine bowl. The researchers even tried bribing the rats, to get them to drink morphine, by dosing the morphine solution with sugar. It should have worked, because rats just love sugar. But it didn't work. The rats wouldn't drink it. The rats just didn't want to get loaded on morphine.
There is a myth going around that dope is such a huge joy that if you try just one dose of it, it will be so pleasurable that you will get hooked for life. We have all heard of the experiments with the lab rats, where rats were put in cages and given levers to press. Each time they pressed the lever, they got a dose of dope. And the rats just pressed the levers all of the time, and stayed high until they died. They wouldn't even stop to eat; they just doped themselves to death. The implication was that the dope was so good, so pleasurable, such an ecstatic high, that the rats couldn't help but get addicted and kill themselves on the stuff.
It turns out that those experiments were all wrong. The researchers who conducted them weren't cheating; they were honest men trying to get good results. They just made one huge mistake: they ignored the true nature of rats. It turns out that rats are very sociable animals, and they just can't stand being held in solitary confinement, like the rats in those experiments were. For both rats and humans, solitary confinement is pure torture.
Some other researchers tried a new experiment: they created a "Rat Park". They fenced a big, natural area, with shrubs and grass, and plenty of space, and put in a small tribe of rats. Then they gave the rats two bowls of water that they could drink from. One contained morphine, and the other didn't. They could drink all they wanted, at any time they wanted. After a few tries, to see what was what, the rats would never drink from the morphine bowl. The researchers even tried bribing the rats, to get them to drink morphine, by dosing the morphine solution with sugar. It should have worked, because rats just love sugar. But it didn't work. The rats wouldn't drink it. The rats just didn't want to get loaded on morphine.
Anonymous A (OP) double-posted this 10 years ago, 6 minutes later[^] [v] #725,696
you will die alone
Anonymous A (OP) triple-posted this 10 years ago, 3 minutes later, 10 minutes after the original post[^] [v] #725,697
Anonymous B joined in and replied with this 10 years ago, 3 minutes later, 13 minutes after the original post[^] [v] #725,698
Mordor is basically just a slower, less interactive Hindu Guy.
NoVn (OP) replied with this 10 years ago, 14 minutes later, 27 minutes after the original post[^] [v] #725,700
@725,697 (A)
So you know why you survive:
Effect of Early and Later Colony Housing on Oral Ingestion of Morphine in Rats,
Bruce K. Alexander, Barry L. Beyerstein, Patricia F. Hadaway and Robert B. Coambs (1980)
http://www.brucekalexander.com/pdf/Rat%20Park%201981%20PB&B.pdf
So you know why you survive:
Effect of Early and Later Colony Housing on Oral Ingestion of Morphine in Rats,
Bruce K. Alexander, Barry L. Beyerstein, Patricia F. Hadaway and Robert B. Coambs (1980)
http://www.brucekalexander.com/pdf/Rat%20Park%201981%20PB&B.pdf
NoVn (OP) double-posted this 10 years ago, 4 minutes later, 32 minutes after the original post[^] [v] #725,701
The present data comprise a better controlled replication of the previously reported housing effect. Colony males in- gested much less morphine solution than isolated males though there was no difference in preference for sweet or bitter-sweet solutions. The data were not as conclusive for females, since there was a trend (short of statistical signifi- cance) toward less intake of bitter-sweet control solution in colony females.
Nonverbal !n9PP8q5SP. (OP) triple-posted this 10 years ago, 51 minutes later, 1 hour after the original post[^] [v] #725,717
I wonder what love does for other diseases (in the broad sense of scientific research) if it can cure meth addiction.
Nonverbal !n9PP8q5SP. (OP) quadruple-posted this 10 years ago, 6 minutes later, 1 hour after the original post[^] [v] #725,718
Housing Effect: Alexander, B. K., R. B. Coambs and P. F. Hadaway. The effect of housing and gender on morphine self-administration in rats. P.tvchopharmacology 58: 175-179, 1978.
Nonverbal !n9PP8q5SP. (OP) quintuple-posted this 10 years ago, 10 minutes later, 1 hour after the original post[^] [v] #725,720
Housing Effect: Males
Males living in the colony at the time of testing ingested much less MHC1 solution than isolated males, but no less of the control solutions. Early isolation appeared to increase morphine intake in the colony-dwellingmales, but the effect reached significance only in Phase 0.15.
No males drank much of the extremely bitter MHCI solution in Phase 1, however, in Phases 0.5, 0.3. and 0.15, colony males (conditions CC and IC) drank less of the morphine-sucrose solution than isolated males (conditions 11 and CI) on all three measures (see Fig. I). Eight of nine Fs for contemporaneous environment in these three phases were statistically significant, five beyond the 0.0001 level. Significance levels for each phase appear in Fig. 1. The effect was greatest in Phases 0.5 and 0.3, in which the isolated males drank 19 times and 6 times as much MHCI solution as the colony males respectively (based on mg/kg data).
There were no significant Fs due to early environment alone, but the early by contemporaneous environment inter- actions in Phase 0.15 were significant for g MHCI solution and mg MHCI/kg body weight. On both measures, colony males which had been isolated early in life (IC condition)tals. To illustrate the nature of the variability, Table 2 pre- sents day-by-day individual data for a representative phase (Phase 0.3, males, mg/kg) and an abbreviated ANOVA summary table.
ACKNOWLEDGEMENTS
We are grateful for help and advice from Wayne Tressel, Kathy Redmond, Joan Foster, Benjamin Staat, Ray Koopman, and Stanton Peele. This research was supported by grants from the Health Promotion Directorate, Health and Welfare, Canada, the British Columbia Ministry of Labour, and from the Steel Foundation, Simon Fraser University.
Males living in the colony at the time of testing ingested much less MHC1 solution than isolated males, but no less of the control solutions. Early isolation appeared to increase morphine intake in the colony-dwellingmales, but the effect reached significance only in Phase 0.15.
No males drank much of the extremely bitter MHCI solution in Phase 1, however, in Phases 0.5, 0.3. and 0.15, colony males (conditions CC and IC) drank less of the morphine-sucrose solution than isolated males (conditions 11 and CI) on all three measures (see Fig. I). Eight of nine Fs for contemporaneous environment in these three phases were statistically significant, five beyond the 0.0001 level. Significance levels for each phase appear in Fig. 1. The effect was greatest in Phases 0.5 and 0.3, in which the isolated males drank 19 times and 6 times as much MHCI solution as the colony males respectively (based on mg/kg data).
There were no significant Fs due to early environment alone, but the early by contemporaneous environment inter- actions in Phase 0.15 were significant for g MHCI solution and mg MHCI/kg body weight. On both measures, colony males which had been isolated early in life (IC condition)tals. To illustrate the nature of the variability, Table 2 pre- sents day-by-day individual data for a representative phase (Phase 0.3, males, mg/kg) and an abbreviated ANOVA summary table.
ACKNOWLEDGEMENTS
We are grateful for help and advice from Wayne Tressel, Kathy Redmond, Joan Foster, Benjamin Staat, Ray Koopman, and Stanton Peele. This research was supported by grants from the Health Promotion Directorate, Health and Welfare, Canada, the British Columbia Ministry of Labour, and from the Steel Foundation, Simon Fraser University.
(Edited 2 minutes later.)
Sheila LaBoof joined in and replied with this 10 years ago, 2 hours later, 3 hours after the original post[^] [v] #725,747
"despite all my rage I am still just a rat in a cage" *shoots smack*
Legend (OP) replied with this 10 years ago, 12 minutes later, 4 hours after the original post[^] [v] #725,749
sadly, did he peak or what ..
(Edited 1 minute later.)
DISooorder (OP) double-posted this 10 years ago, 2 hours later, 6 hours after the original post[^] [v] #725,799
bump.
Anonymous A (OP) triple-posted this 10 years ago, 1 day later, 2 days after the original post[^] [v] #726,369
@OP
LOL
LOL
dog (OP) quadruple-posted this 10 years ago, 2 minutes later, 2 days after the original post[^] [v] #726,370
got to take a fucking shower dammit
Symptom !n9PP8q5SP. joined in and replied with this 10 years ago, 3 weeks later, 3 weeks after the original post[^] [v] #731,130
bump.
