Minichan

Topic: ATTN: kook

WSD !m2cp3rR5zw started this discussion 11 years ago #44,651

https://en.wikipedia.org/wiki/Schizophrenia_and_the_Effects_of_Estrogen_on_Schizophrenia#Estrogen_as_a_treatment

Green !BEERiVqJJw joined in and replied with this 11 years ago, 1 minute later[^] [v] #589,564

Holy shit, it's Walter.

Anonymous C joined in and replied with this 11 years ago, 21 seconds later, 2 minutes after the original post[^] [v] #589,565

Calm down, Walt.

Kook, I am going to pre-emptively tell you to calm down too. Neither of you needs to get so worked up over what hormones people are putting into themselves.

WSD !m2cp3rR5zw (OP) replied with this 11 years ago, 4 minutes later, 6 minutes after the original post[^] [v] #589,566

Major advances have been made in improving the lives of schizophrenics since Paul Eugen Bleuler coined the term in 1908. From that time forward schizophrenia has been observed as a legitimate disease and steps have been taken to improve the lives of people with the disorder. Estrogen was found to blunt the effects of schizophrenia and improve the symptoms in both men and women. Overall, estrogen supplements were found to have the best effect on women with schizophrenia. This discovery has had a major impact on the lives of those suffering from schizophrenia.

My opinion: schizophrenia is a codeword for estrogen deficiency.

brie joined in and replied with this 11 years ago, 2 minutes later, 8 minutes after the original post[^] [v] #589,567

@previous (WSD !m2cp3rR5zw)
Now this would make a lot of sense!

The 'loom factories' can shut down now, but that is a schizoid term for a conspiracy.

kook !!b4KbSydQS joined in and replied with this 11 years ago, 1 hour later, 1 hour after the original post[^] [v] #589,589

@589,565 (C)
Fuck off

kook !!b4KbSydQS double-posted this 11 years ago, 50 seconds later, 1 hour after the original post[^] [v] #589,591

@589,566 (WSD !m2cp3rR5zw)
Wow, no wonder she's doing so much better! Tell her that I asked about her, please.

WSD !m2cp3rR5zw (OP) replied with this 11 years ago, 14 minutes later, 1 hour after the original post[^] [v] #589,602

@previous (kook !!b4KbSydQS)
That I have. Also, people with schizophrenia are known to suffer from osteoporosis, and osteoporosis can be treated very well with estrogen (and/or testosterone).

http://www.ncbi.nlm.nih.gov/pubmed/15625215
The male patients with schizophrenia in this study suffered from low bone density. This finding as well as other reports lend support to directing more attention to bone metabolism in patients with schizophrenia, although there is no universally accepted screening policy to identify individuals at high risk for osteoporosis.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566242/
Osteoporotic fractures have considerable adverse effects on general health, subjective well being, the ability to engage in healthy lifestyle behaviors, and increased healthcare costs. A higher prevalence of osteoporosis or lower BMD is widely reported in schizophrenia, and needs to be recognized as an important comorbidity. Prevention, early detection, and intervention are required. Although the effect of antipsychotic-induced hyperprolactinemia seems be one contributing factor for low BMD, others, especially those related to poor lifestyle behaviors, may have an even bigger impact. Moreover, since osteoporosis develops over time, sufficiently large, longitudinal studies are required to examine contributors of accelerated BMD loss. To date, there is only limited evidence for the osteoporosis-producing effects of antipsychotics. Better designed studies, including studies utilizing BTM, may further clarify the relationship between antipsychotics and bone metabolism. Until such data are available, the main clinical focus should be on promoting healthy diet and exercise as well as adequate sun exposure. However, if hyperprolactinemia develops, hypogonadism needs to be ruled out via assessment of menses or sex hormone levels, or a change of antipsychotic treatment to a less prolactin-elevating agent should be considered, especially when sexual and/or reproductive system dysfunction is present.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC381441/
It seems more likely that E inhibits bone resorption by inducing small but cumulative changes in multiple E-dependent regulatory factors, as shown in Figure Figure1.1. Of the E-dependent factors affecting OC formation, TNF-α and the OPG/RANKL/RANK system may be most important, whereas TGF-β and the OPG/RANKL/RANK system may have greater effects on OC activity and apoptosis. Clearly, more data are needed, especially on cytokine changes in the bone microenvironment of women with early postmenopausal bone loss or postmenopausal osteoporosis.

I believe that estrogen replacement therapy is the safest and one of the most effective treatments of schizophrenia, and it also promotes healthy bones among those with schizophrenia. It would be stupid to pump them with drugs all day when we can just give estrogen and lower doses of antipsychotics and send them on their way.
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